10 Surprising Masteron Side Effects

What is Masteron? Masteron, or Drostanolone Propionate, is an exotic androgenic and anabolic steroid with quite a history. Unfortunately, there are plenty of Masteron side effects.

It was initially used to treat breast cancer in women, but it is no longer marketed.

Nowadays, it is used for its anabolic properties. Anabolic steroids enhance muscle tissue growth by mimicking the natural testosterone in the body.

Masteron is the more commonly used name. However, it is also sold under the brand names, Drolban and Masteril.

If you plan on using any hormone-altering drug, you will need all the information you can get. In this article, you will understand how this drug works and the possible Masteron side effects backed by studies.

Sounds good? Let’s get started with how the product works.


How it Works

As earlier stated, anabolic steroids or anabolics stimulate muscle growth by mimicking natural testosterone. This is popularly known as bulking up.

It is popularly known to aid in muscle hardening and growth. It also has anti-estrogen properties.

Masteron can remain in the body anywhere from a couple of days to a year, depending on the frequency of use.

Such steroids are popular for muscle growth, definition, and increased endurance and functional strength. Moreover, no research confirms its effectiveness in improving skill or agility.

Masteron comes in two forms;

  • Drostanolone Propionate
  • Drostanolone Enanthate

Each of these forms comes with its pros and cons.

1. Drostanolone Propionate

This is the original form of Masteron.

Masteron propionate is effective as an anti-estrogen and anabolic. However, it is not as potent as the more conventional steroids on the market.

However, it is still effective in aiding muscle growth.

Masteron propionate chemical composition increases the drug’s anabolic potency and slows its metabolism. That explains why it can stay in the body for up to a year.

2. Drostanolone Enanthate

Masteron enanthate is a longer ester of the Masteron molecule. This means it stays in the body even longer than Masteron propionate.

The implication is that you can use less frequent doses of enanthate than propionate, but the doses will have to be larger.

Masteron enanthate also works well with testosterone enanthate, according to users.

Now that we know what Masteron is all about, let me give you a quick run-down of the benefits before we get to the Masteron side effects.

Benefits of Masteron

There are several benefits you might experience if you use Masteron. In this article, we will focus on the more sought-after workout-related benefits.

These include;

1. Muscle Hardening and Growth Stimulation:

This is possibly one of the most noticeable effects of Masteron. It is ideal for bodybuilders and athletes who want a more ‘filled out’ look.

According to a study published in the National Library of Medicine, anabolic steroids can lead to strength gains of about 5-20% of the initial strength and up to 5kg increments of body weight.

Moreover, the product can boost the growth of lean muscle mass.

Androgenic anabolic steroids can also prevent bone breakdown and increase hypertrophy.

2. Improved Energy Levels:

Users report having increased energy levels at the gym. This is because Masteron helps increase metabolism, thus increasing the energy output of your cells.

3. Helps in Cutting:

This is controversial since it is more known for bulking than cutting. However, many users report that it is more effective in cutting than bulking.

This shows that it comes down to the user’s goals. Masteron aids the speed of the journey.

Masteron does not have many benefits compared to more conventional steroids. Luckily this also means that Masteron side effects are not as many.

Let us get started with the possible Masteron side effects.

Masteron Side Effects

1. Acne Vulgaris

Acne Vulgaris is the medical name for common acne. It is an inflammation of the oil glands in your skin and hair follicles.

It is usually caused by a bacterium(Propionibacterium acnes) alongside other factors. Steroid acne is similar to typical acne.

A study shows that anabolic steroid use, such as Masteron, makes the oil glands susceptible to this bacteria and inflammation.

2. Aggressive Behavior

Another Masteron side effect is aggressive behavior. Steroid use may affect your brain’s limbic system, which controls your mood and demeanor.

Reports indicate anabolic steroids increase irritability, although findings are mixed due to the personality traits of steroid users. i.e., antisocial and personality disorders.

This suggests that it is unclear whether the steroid causes aggression or whether it is an inherent characteristic of steroid users.

3. Low Sperm Count/ Infertility

Long-term use or misuse of Masteron may be detrimental to sperm quality parameters and overall fertility.

Although users try methods such as ‘stacking’ and ‘cycling’ to bypass the side effects of misuse of anabolics, there is no scientific evidence that sperm quality will not be affected.

4. Elevated Blood Pressure

A study shows that daytime and nighttime blood pressures of users of anabolics like Masteron have been considerably higher than those of non-users.

This is another addition to possible Masteron side effects.

According to the study, anabolic steroids cause systolic blood pressure increase and hypertension that may be associated with an increased risk of cardiovascular disease.

5. Depression of Cholesterol Levels

Another Masteron side effect is reduced cholesterol levels.

The repeated usage of anabolic steroids causes depression in serum high-density lipoprotein HDL, HDL2, and HDL3 cholesterol levels.

HDL (high-density lipoprotein) cholesterol, popularly known as “good” cholesterol, absorbs ‘bad’ cholesterol in the blood and returns it to the liver.

High levels of HDL cholesterol can lower the risk of heart disease.

6. Low Self Esteem

Yet another Masteron side effect and anabolics in conjunction is low self-esteem. This may vary from person to person.

There is a surprising amount of stigma that comes with using anabolics. The premise is that the gains gotten while using them are only credited to the steroid.

Another study suggests that persons using anabolics are more prone to self-image disorders and depression.

7. Stunted Growth in Teens

Anabolic use can harm the development of teens due to hormonal changes.

A study shows that teen boys that use steroids may grow breasts and have smaller testicles due to hormonal imbalance.

In teen girls, it may cause male patterns like facial hair and a deepened voice. It may also halt puberty in both genders, so you don’t increase in height.

8. Depression

Depression on withdrawal of use is another Masteron side effect. This is, however, seen in fewer users.

This may be attributed to the ‘sense of power’ and increased energy levels that users associate with anabolic use.

9. Fatigue

Another Masteron side effect usually experienced after withdrawal, especially after long-term use, is fatigue.

The absence of anabolics causes a decline in energy levels since the body is already accustomed to them. This leads to fatigue even when doing simple tasks.

10. Decreased Sex Drive

Anabolics like Masteron are linked with a significant increase in libido.

A study published in the National Library of Medicine suggests that the discontinuation of the use of steroids may cause erectile dysfunction as well as libido loss.

This is because the natural testosterone levels may also be lowered due to the withdrawal.


Hormone-altering drugs like Masteron are bound to have side effects. However, Masteron’s side effects are more forgiving than its steroid counterparts.

If you are looking for a potent anabolic with relatively low odds of having side effects, then Masteron is a decent pick.

Nevertheless, sticking to natural supplements and a good old-fashioned workout regime is preferable. The gains will come eventually if you work smart. It’s only a matter of time.

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