10 Little-Known Glutathione Injection Side Effects 

If you are considering taking glutathione to improve your health, it’s important to know the glutathione injection side effects. This article will provide answers to those questions. Please read on.  

Glutathione is an antioxidant or tripeptide that consists of three acids:

  • Cysteine is a non-essential amino acid important for making protein and collagen. It’s found in hair, skin, and nails.
  • Glycine is an amino acid that helps build proteins necessary for tissue and hormone maintenance.
  • Glutamic acid is an amino acid used in the formation of proteins. The brain turns it into glutamate, which helps nerve cells in the brain send and receive information among cells. It also plays a role in learning and memory.

The liver creates it, and is essential for many biological processes.

In addition to helping build vital proteins and compounds, glutathione also aids in tissue repair and growth. It also supports healthy immunological function. 

How does glutathione injection work? 

Generally speaking, glutathione minimizes superficial aesthetic flaws, brightens the skin, and even out uneven skin tone.

It can help with sudden breakouts or cystic acne as well. By removing free radicals and toxins from the body, glutathione injections diminish hyperpigmentation, acne, wrinkles, sun spots, and melasma.

Additionally, it has anti-inflammatory qualities. 

Glutathione must be administered through frequent injections to be effective. Oral glutathione supplementation offers minimal benefits; hence, they are useless.

It is, for this reason, many people prefer injections. It’s critical to remember that the FDA does not approve Glutathione injections. Also, it advises against taking skin whitening injections for safety reasons.

All in all, you must decide whether or not to administer this injection because no formal scientific studies have confirmed its efficacy. 

Is glutathione good for skin whitening? 

Most studies and research indicate that glutathione injection tends to encourage skin whitening.

Although this injection will prolong the effects, you need booster injections to keep them from wearing off. These dose boosters are available as glutathione tablets or injections.

The outcomes will be more potent if this technique is coupled with other aesthetic procedures like laser skin lightening. 

What are the benefits of glutathione injection? 

The common benefits of glutathione injection include boosting energy, stamina, body purification, and—most importantly—better, whiter skin.

However, keep in mind that these advantages are not supported by science. Rather, they are based on customer reviews.

For instance, some Asian women who have used the injection report feeling more energized, having stronger immune systems, more sexual desire, and having brighter, whiter, more beautiful skin.

However, despite those claims, no studies currently demonstrate it inhibits the tyrosinase enzyme, which is essential for melanin production. 

Also, note that taking glutathione intravenously helps to improve the speed by which digestion occurs.

Besides, the injections ensure complete and quicker absorption of antioxidants present in glutathione into the bloodstream. This will not be the case if one takes glutathione orally.  

Some additional glutathione benefits include: 

1. Skin Radiance 

Glutathione can accelerate cell renewal among young and older people. These new cells create a smooth surface that reflects light and can restore your skin’s glow.

Besides, it improves cell turnover rate, giving you a rejuvenated face every month. Note that the average cell turnover rate is once per twenty-eight days.

It slows down significantly once in 45 days by the time an individual is in their 40s and keeps slowing as they age. Normally, this slowdown in cell turnover rate can make a person’s skin look bland.

Hence glutathione reverses this effect. 

Also, glutathione regulates healthy blood circulation, a crucial internal aspect of glowing skin. The skin receives nutrition and nourishment through increased blood flow.

It purges impurities and imparts a lovely rosy glow to the complexion. 

2.  It improves liver health. 

Glutathione, as an antioxidant, improves liver health. A lack of antioxidants in the liver can lead to the death of liver cells.

However, in the presence of antioxidants, like glutathione, the destruction of such cells reduces significantly. Hence, it improves the liver’s health.  

3. Skin whitening 

Glutathione has specific properties, making it unique for skin whitening. Processing the chemicals and proteins that your bodily systems require aids in tissue repair and growth.

It covers every aspect of your immune system’s operation. 

Due to its role as an antioxidant in cosmetics, glutathione aids in removing toxins from the body by lightening skin and removing scars, dark spots, acne, and blemishes visible on the face.

Your skin glows and becomes brighter than ever after that technique. 

What are the glutathione injection side effects? 

A glutathione injection might have several negative effects, just like any other cosmetic procedure. Depending on the dosage, the side effects can range from mild to severe.

This is why you should have a competent and experienced medical practitioner deliver the glutathione injection to prevent or lessen the severity of any side effects. 

Patients receiving a significantly higher dosage than required risk experiencing catastrophic adverse effects like blood poisoning or kidney failure.

In addition to this, if more than 5 grams of glutathione are administered, the following additional negative effects of glutathione injection may also manifest: 

  • Hair loss. 
  • Chest pain. 
  • Unhealthy weight gain. 
  • Breathing problems.  
  • Eye disorder.  
  • Hair whitening.
  • Diarrhea.  
  • Skin allergies.  
  • Nausea.  

Studies show that inhaled glutathione can lead to breathing problems for people with asthma. Research is limited on how the injection can affect people with pre-existing respiratory conditions.

In addition, research shows that prolonged use of glutathione supplements can result in allergic reactions such as cramping, bloating, and, occasionally, a rash.

Some studies show that long-term use of glutathione can lead to zinc deficiency. Due to this glutathione injection side effect, you may need to discuss adding zinc supplements to your diet with your doctor.

Zinc is an important mineral for immunity support, wound healing, and the development of a baby during pregnancy.

A zinc deficiency can lead to loss of appetite, infections, impotence, vision problems, changes in nail color, and wounds taking too long to heal.

What to expect from glutathione injections 

The glutathione injection process is the same as for any other shot or immunization. Yes, it can be uncomfortable and painful, but it’s just a small annoyance. 

If you are new to this supplement, experts advise taking 300 to 600 mg within the first three weeks. After the fourth week, you can begin lowering the treatments to once every week. Expect skin benefits within six weeks. 


Glutathione injections can resolve your uneven skin tone. However, you must be cautious because it is not FDA-approved. Furthermore, there is little evidence to determine the safe glutathione dosage.

Please remember that using the appropriate dosage can bring maximum benefits. Also, keep in mind that even natural supplements may be insecure.

Consider the product label and consult a healthcare professional before using it. Additionally, it is advised that you only administer the injection while a doctor is watching.

Please be aware that glutathione products are primarily intended for medicinal use, not cosmetic use. 

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