10 Scary Lumbrokinase Side Effects You Should Be Aware of 

Even though Lumbrokinase is safe to use, it has some side effects. Read on to find out what those side effects are.

Lumbrokinase is an enzyme preparation extracted from earthworms. Earthworms have been used traditionally as medicine in countries such as China, Japan, and Korea. 

According to this study in PubMed, Lumbrokinase enzymes are effective for curbing thrombosis. 

This enzyme has fibrinolytic and proteolytic properties, thus preventing blood clotting as it breaks down fibrinogen, a protein responsible for blood clotting. 

Though blood clotting may be important in the body to heal wounds, it is necessarily not required in the veins as it might lead to stroke. 

The main function Of Lumbrokinase 

Lumbrokinase enzymes are recognized as fibrinolytic agents that can treat various conditions associated with thrombosis. 

Lumbrokinase may greatly benefit those suffering from conditions related to adrenal fatigue.  

Adrenal fatigue is associated with the following health issues, hormone imbalance, diabetes, fibromyalgia, heart disease and some psychological disorders,  

Moreover, the benefits of lumbrokinase are further by the subtopics below. 

Lumbrokinase And Adrenal Fatigue 

Lumbrokinase is mainly used to relieve adrenal fatigue. Its antioxidative, anti-ulcer anticarcinogenic, and antibacterial properties have made this possible.

1. Fighting Inflammation

in addition, lumbrokinase also addresses inflammation issues. This is a common problem that is contributed by adrenal fatigue. 

Inflammation is normally preceded by an increase in fibrinogen and unhealthy blood clotting; this is associated with increased adrenal fatigue.  

It is, therefore, necessary to reduce the inflammatory response as it can contribute to chronic diseases, such as heart disease, diabetes, obesity, cancer, and Alzheimer’s disease 

2. Antioxidant Properties

Antioxidants protect the body from the oxidative process and damage from free radicals.

3. Gastric Health

lumbrokinase also has antibacterial properties and supports gastric health by reducing bad bacteria in your gastrointestinal tract. 

Gut health affects the absorption of nutrients during the healing process, hence should be prioritized. 

In addition, lumbrokinase protects gut health by decreasing stomach acidity, thus preventing the formation of ulcers.

4. Diabetic Nephropathy

Diabetic nephropathy refers to kidney damage due to diabetes. This makes the kidney unable to perform its blood-filtering abilities, which leads to protein accumulation in the urine. 

Studies have shown that lumbrokinase may help with diabetic neuropathy by improving kidney function. Kidney dysfunction is often caused by adrenal fatigue, toxic buildup, and inability to eliminate toxins.

5. Stroke

According to research, lumbrokinase may help in recovery from ischemic stroke. A blockage causes this type of stroke in blood vessels in your brain.  

Such a blockage results in brain cells dying off as it prevents oxygen from reaching the brain. However, check with your doctor regarding the type of stroke because you don’t want to take a blood thinner if you have a hemorrhagic stroke. 

Lumbrokinase is safe and effective for treating acute ischemic stroke by lowering blood viscosity, preventing reperfusion damage, and reducing neural deficits.

6. Coronary Artery Disease

Coronary artery disease refers to the blockage of coronary arteries. This is usually due to the buildup of cholesterol and plaques on the inner walls of the streets.  

This condition may result in inadequate blood supply to the heart, which means it does not receive the oxygen and nutrients it needs to work properly. 

Evidence suggests that lumbrokinase may help with coronary heart disease and its symptoms by improving blood flow, reducing arrhythmia, and improving cardiovascular blood markers.

7. Oncology

Most cancer patients are hypercoagulable and prone to develop venous thromboembolism. Thus, lumbrokinase is used to prevent or treat bleeding associated with cancer.  

Lumbrokinase is one of the anticoagulants that limit the growth of tumors and metastasis. This has, however, been proven only in vitro. 

Trials on the human body are yet to be accomplished, which could be a good advancement for the future.  

How do you use lumbrokinase? 

Take one capsule daily on an empty stomach. 

Does lumbrokinase dissolve blood clots? 

As stated in Amazon, Lumbrokinase dissolves blood clots and is an effective tool for treating and preventing cardiovascular disease, reducing blood viscosity or thickness, and balancing clotting ability.  

Balanced blood viscosity allows blood to flow more freely throughout the body, especially to the muscles and tissues, which may help to decrease muscle cramps and pain caused by hypercoagulation. * 

Can I take lumbrokinase and aspirin together? 

Lumbrokinase has been proven to be effective when taken with aspirin. You can also take it with coumadin and heparin blood thinners without the added risk of bleeding.  

It is also effective when taken with aspirin for those patients suffering from gastrointestinal reactions with aspirin alone. 

What are some of the side effects of lumbrokinase? 

According to some of the reviews from Amazon, lumbrokinase does not have scary side effects that may require serious medical attention. 

Although it dissolves fibrin clots, it does not lead to excessive bleeding or blood loss. 

Some of the mild side effects associated with lumbrokinase include; 

Slows down prothrombin time 

Lumbrokinase may slow done prothrombin time, a condition also known as Prothrombin deficiency. It involves slowing down of blood clotting process. 

This condition is mostly witnessed by patients who have suffered injuries or have undergone surgeries. 

Moreover, prothrombin deficiency can cause prolonged heavy bleeding during menstruation; the serious complications might include bleeding into the joints, brain, and other internal organs, especially after surgery. 

Therefore, it is important to consider the patient’s medical history before surgery. I.e., if they are taking lumbrokinase. 

Black stool  

The black stool could signify bleeding in the upper digestive tract. Lumbrokinase may contribute to this; however, it is not a common side effect. 

Other minor side effects include. 

  • Dizziness. 
  • Skin itching 
  • Diarrhea
  • Causes nausea 

These side effects are mainly due to allergies; hence talk to your doctor before obtaining a prescription. 


In conclusion, the side effects of lumbrokinase are not as common as other supplements. On the other hand, they are not serious. Its benefits are much more than side effects. 

Lumbrokinase is a safe supplement. However, there are some exemptions, and these include pregnant women, lactating women, and children.  

This is because no sufficient evidence backing its suitability for such persons. In addition, it would be important to consult your prescriber when you experience the above side effects. 

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