10 Frightening Tri-Lo-Sprintec Side Effects

Tri-Lo-Sprintec side effects have been reported, which you can read about when you buy the product.

Tri-Lo-Sprintec is also referred to as Tri-Lo-Mili (28 days), Tri-Lo-Estarylla (28 days), or Tri-Lo-Marzia (28 days).

It’s also known as Norgestimate (Ethinyl Estradiol) (28 days) and Tri-Vylibra Lo (28 days). The medication Tri-Lo-Sprintec is used to stop ovulation and prevent pregnancy. 

Additionally, Tri-Lo-Sprintec is used in acne treatments. Tri-Lo-Sprintec belongs to a class of medications known as oral contraceptives.

It’s a combination of estrogen and progesterone. Tri-Lo-Sprintec may cause well-known side effects as you try to prevent ovulation or pregnancy.

However, the side effects may improve as your body adjusts to the medication. If you continue to experience these symptoms or if they get worse over time, you should tell your doctor immediately. This is the best course of action.

Here are ten frightening Tri-Lo-Sprintec side effects you should be aware of.

10 Tri-Lo-Sprintec side effects

#1. It Can Cause Headaches

One of the most common Tri-Lo-Sprintec side effects is experiencing migraines after taking the contraceptive. Therefore, it is best to contact your provider immediately if you experience new or worsening migraines or headaches.

Moreover, if the headache keeps coming back or is severe, please make sure you get checked. According to the medical news today medical team, “Estrogen levels drop abruptly when an individual takes inactive pills.” The action can trigger migraines and other headaches.

“When taking a birth control pill, people who notice a sudden increase in headaches probably react to this hormonal shift.”

#2. It Can Cause Nausea

Nausea is an additional Tri-Lo-Sprintec side effect you will also experience. When you take a Tri-Lo-Sprintec tablet, the tablet’s estrogen results in queasiness that irritates your stomach lining.

Additionally, you will feel dizziness after taking this birth control pill, which promotes nausea. The estrogen levels are likely to cause stomach upset, hence symptoms like nausea.

“The pill’s nausea should subside within a few days. Schedule a visit to the doctor if the nausea continues. Your appetite and weight can be affected by persistent nausea.

“You might have to change to one more pill or an alternate type of contraceptive pill,” says Debra Rose Wilson, medical advisor at Healthline.

#3. It May Result in Your Mood Changes

Another common Tri-Lo-Sprintec side effect is experiencing mood changes. After taking the pills, your moods will worsen, and you may experience feelings of depression.

You’ll also notice that you’re easily irritated. If you find the feelings bothersome, it’s best to report them to your care team.

#4. It Can Cause Breast Changes

After taking Tri-Lo-Sprintec, you’ll probably experience breast changes such as breast tenderness and enlargement. Additionally, you can experience breast pain.

The presence of both estrogen and progestin causes the changes. When you experience breast tenderness, you’ll feel a heavy or sore feeling that may spread to your armpit or upper arm.

The feelings are experienced in both breasts and are usually at their worst right before your period. After hormonal birth control use, breast changes may result from increased estrogen and progesterone levels.

Your breasts may become more prominent and tender, necessitating an additional bra size, says Christine Masterson, Director of the Women and Children service line at Summit Health.

#5. It Can Cause Vomiting

Besides nausea, you’ll experience vomiting. Nausea is feeling dizzy, but you don’t vomit.

Someone else will use the pill and vomit. The side effects differ. As a result, you will experience forcible stomach emptying, making you vomit.

The stomach is forced to overcome the pressures that typically exist to keep food and secretions in the stomach. It’s possible for the vomiting to subside over time, but there are ways to reduce or eliminate it.

#6. You Can Observe an Increased Vagina Discharge

Unusual vaginal discharge is one of the most frequently reported Tri-Lo-Sprintec side effects. The Tri-Lo-Sprintec pill thickens your cervical fluid to prevent sperm from entering the uterus.

This can change the color or texture of your discharge, which can change how it looks or feels. You’ll experience a brown, rusty vaginal discharge.

Additionally, the discharge may start producing some odor. Furthermore, you may experience vaginal itching or irritations resulting in vaginal discomfort. 

#7. You May Experience Decreased Sex Drive

When you experience changes in vaginal discharge when taking the Tri-Lo-Sprinec pill, it can affect your sexual drive. Experiencing less sexual drive after taking the medication is another Tri-Lo-Sprintec side effect.

Taking the Tri-Lo-Sprintec reduces vaginal lubrication, which changes the nature of your virginal discharge. This can affect your sexual intercourse.

It is well known that oral contraceptives cause the liver to produce more Sex Hormone Binding Globulin (SHBG). This protein attaches to testosterone and stops it from being utilized by the body, which lowers sex desire, says Sophia Yen, CEO, and co-founder at Pandia Health.

#8. It Results in Changes in Weight or Appetite

Tri-Lo-Sprintec, like many other birth control pills, can make women feel hungry more often. Thus, it prompts excess calorie consumption and weight gain.

Fortunately, the Tro-Lo-Sprintec side effect is brief since it is caused by fluid retention rather than excess fat. Therefore, the minimal weight gain may subside within two to three months.

In the first month of using Tri-Lo-Sprintec, you may gain 1-4 pounds. However, since these few potential pounds are typically water weight rather than fat, they will disappear quickly.

#9. It Can Cause Irregular Bleeding

Irregular menstrual cycles are among the most common Tri-Lo-Sprintec side effects. After or while using the Tri-Lo-Sprintec, you’ll experience bleeding between menstrual periods (spotting).

Additionally, you can have missed or irregular periods. This will primarily occur during the first few months of use of Tri-Lo-Sprintec.

Dr. Andrei Marhol, General practitioner and medical advisor, Flo Health Inc., confirms that a common cause of breakthrough/irregular bleeding is hormonal contraception. This causes your body to adjust to different hormone levels.

In addition, it can happen if you’ve switched to another method of contraception. 

#10. It Can Lead to the development of Dark Patches on The Skin

Last but not least, dark patches are another Tri-Lo-Sprintec side effect. You notice dark patches on your face after taking the Tri-Lo-Sprintec pill.

Furthermore, dark patches can also appear in all sun-exposed areas. We said Tri-Lo-Sprintec is used in acne treatment.

Additionally, it helps keep your skin smoother and softer. However, because the medication alters the quantity and type of hormones the body produces, Tri-Lo-Sprintec may exacerbate melasma. 

Tri-Lo-Sprintec, like most birth control pills, contains progestin and Ethinyl estradiol, a type of estrogen. The chemicals are sufficiently strong to create a reaction in melasma-inclined skin, causing the equivalent smeared, hyperpigmented look.

Talk to the doctor who gave you the birth control pills if you’ve noticed an increase in the severity of your melasma since taking them. 


There is more to using the Tri-Lo-Sprintec birth control pill. Having listed the 10 Tri-Lo-Sprintec side effects, we have seen that some can be severe while others can deteriorate your health drastically.

Therefore, I recommend you consult a physician before using Tri-Lo-Sprintec. You will likely notice that the best option is to omit a birth control method with severe side effects.

Just remember to use a backup form of birth control while on Tri-Lo-Sprintec. If you have any of the listed Tri-Lo-Sprintec side effects, do not take them. First, talk to your healthcare provider about other birth control options.

This is especially if you are concerned about Tri-Lo-Sprintec side effects.

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